10 Luxe Hand & Body Cream
Your hands, arms, elbows, and knees age just like your face, but most people ignore them. This is the only body cream with patented Age-Repair Defensins® peptides, bringing defensin renewal technology beyond your face for the first time. Clinically studied and shown to help visibly improve the appearance of firmness, hydration, texture, and density in just 6 weeks.
Why PRO Exclusive?The PRO Exclusive formulation features an enhanced concentration of Age-Repair Defensins® peptides not available in our retail formulation, specifically for body skin. In DefenAge's peer-reviewed clinical research, enhanced defensin concentrations have been shown to support visible improvement in both the surface and deeper layers of the skin. Available only through your provider's office.
Your Body Deserves the Same Care as Your Face
If you're investing in your facial skincare but ignoring everything below the neck, you're only doing half the job.
Dry, rough hands
Your hands show your age faster than almost anything else. Constant washing, sun exposure, and neglect leave them dry, rough, and spotted.
Deep, lasting hydrationCrepey arms and forearms
The skin on your arms has thinned and lost its bounce. It looks papery, wrinkled, and fragile. Regular body lotion isn't addressing the problem underneath.
Supports improved elasticityWrinkled elbows and knees
These neglected areas age the fastest. The skin is thicker, dryer, and more prone to deep creasing. Most body creams barely make a dent.
Visibly smoother and softerDullness and uneven tone
Your body skin has lost its glow. Sun damage, age spots, and uneven pigmentation make your arms and legs look older than you feel.
Brighter, more even appearanceThinning, fragile skin
Your skin bruises more easily. It tears and takes longer to heal. The density and thickness that used to protect it have diminished over time.
Supports skin density and firmnessAshiness and discomfort
Your skin feels uncomfortable. It's ashy, tight, and never looks or feels truly moisturized no matter what you put on it.
Comforts and replenishesWhat Patients Are Seeing
Results from a peer-reviewed clinical study published in the Journal of Cosmetic Dermatology. Hands, forearms, elbows, and knees tested over 6 weeks.
"Subjects reported significant improvement across all subjective skin domains. Objective measurements demonstrated significant improvement in skin architecture including elasticity, hydration, and skin thickness."— Eggerstedt et al. Journal of Cosmetic Dermatology, 2023
See the Difference
Clinical study photos from the published Journal of Cosmetic Dermatology trial. Photographed at baseline and after 6 weeks of twice-daily use.
The Only Body Cream With Defensin Peptides
Regular body lotion hydrates the surface. This cream supports renewal underneath.
Renewal, not just moisture
Contains patented Alpha-Defensin 5 and Beta-Defensin 3 peptides, the same type of defensin peptides used across the DefenAge PRO Exclusive line. While other body creams coat the surface, this one supports your skin's own renewal process underneath the hydration layer.
Clinically studied results
The body cream was tested in a peer-reviewed clinical study and showed measurable improvements in elasticity, density, hydration, and thickness in just 6 weeks. Real data, real results.
Head-to-toe defensin coverage
Your hands, arms, elbows, knees, and decolletage age too. Now you can bring defensin peptide technology beyond your face for the first time. One consistent approach from head to toe.
Full Ingredient List — 10 Luxe Hand & Body Cream PRO
▾Simple. Morning and Night.
Start with the Masque (weekly)
Once or twice a week, use the 2-Minute Reveal Masque on your hands, arms, elbows, and knees before applying the cream. This clears surface buildup so the cream absorbs more effectively.
Optional but recommendedApply the cream
Apply to hands, arms, elbows, knees, and any areas of concern. Massage in gently. Use morning and evening for best results.
Morning & eveningBe consistent
The clinical study showed measurable results in 6 weeks with consistent twice-daily use. Your body skin renews slower than your face, so give it time and stay consistent.
6 weeks to visible resultsReady for Head-to-Toe Renewal?
The 10 Luxe Hand & Body Cream PRO Exclusive is available only through authorized medical aesthetic providers. Find one near you.
Pairs Perfectly With
Bestseller8-in-1 BioSerum
Defensin renewal technology for your face. Complete the head-to-toe approach.
Learn More →
2-Minute Reveal Masque
Use on hands, arms, elbows, and knees before the cream for better absorption.
Learn More →
