


3D Eye Radiance Cream
The skin around your eyes is thinner, more sensitive, and ages faster than anywhere else on your face. Crow's feet, puffiness, dark circles, and creasing show up here first. This cream brings patented defensin peptides to the delicate skin around your eyes, visibly improving the look of the delicate eye area without irritation.
Why PRO Exclusive?The PRO Exclusive formulation features an enhanced concentration of Age-Repair Defensins® peptides not available in our retail formulation, specifically formulated for the delicate skin around the eyes. In the Fabi/Taub 2023 peer-reviewed clinical study, this enhanced concentration was shown to support visible improvement in both the surface and deeper layers of the skin around the eyes. Available only through your provider's office.
What Are You Seeing Around Your Eyes?
If you've noticed any of these, the 3D Eye Radiance Cream was designed for exactly what you're experiencing.
Crow's feet getting deeper
The lines at the corners of your eyes that used to disappear when you stopped smiling now stay permanently. They're deeper every year and visible even at rest.
Supports smoother, firmer skinDark circles and puffiness
You look tired even when you're not. The skin under your eyes is thin, dark, and puffy. Concealer only does so much and it's getting worse.
Brighter, more refreshed appearanceFine lines and creasing
Fine lines across the under-eye area and eyelids. The skin looks crepe-like and fragile. Foundation settles into every crease and makes it worse.
Visibly smoother textureLoss of firmness
The skin around your eyes has lost its bounce and elasticity. The brow area feels heavier and the under-eye area looks hollowed out or saggy.
Visibly firmer, more resilient-looking skinSensitivity and redness
Your eye area reacts to everything. Other eye creams sting or cause irritation. You need something effective but gentle enough for the most sensitive skin on your face.
Gentle, no irritation reportedDryness and dull skin
The eye area looks flat and dehydrated. It lacks the brightness and glow it used to have. Products you apply seem to evaporate instead of absorbing.
Replenishes moisture and clarityWhat Patients Are Seeing
Results from a peer-reviewed clinical study on the DefenAge 3D Eye Radiance Cream published in the Journal of Cosmetic Dermatology. Periocular area tested over 6 weeks.
"The use of a defensin-containing eye cream led to a statistically significant improvement in patient-reported outcomes of skin quality. The largest improvements were in crow's feet, redness, and sensitivity."— Berens, Ghazizadeh. Journal of Cosmetic Dermatology, 2020


Built for the Most Delicate Skin on Your Face
Your eye cream shouldn't just moisturize. It should renew.
Visible results, not just concealment
Most eye creams temporarily hydrate or use light-diffusing tricks to mask the problem. This cream contains patented defensin peptides that visibly improve the look of the delicate eye area where aging shows first. Real visible results, not just temporary coverage.
Cooling Tip Technology
The metal applicator tip provides a soothing, cooling sensation while delivering the cream precisely where you need it. Hygienic, gentle, and no tugging on delicate skin. You'll feel the difference the first time you use it.
Safe for the most sensitive area
No retinol, no harsh acids, no irritation. Safe for contact lens wearers, safe on the upper eyelid and under the eyes. Can also be used after aesthetic treatments like microneedling, lasers, and fillers around the eye area.
Full Ingredient List — 3D Eye Radiance Cream PRO
▾Gentle Application. Morning and Night.
Cleanse
After cleansing, leave skin slightly moist from rinsing. The eye cream absorbs best on moist skin.
Apply while skin is still moistApply with the Cooling Tip
Pump a drop of cream onto the metal applicator. Lightly dab three dots of cream above and below each eye. Using the applicator, gently massage the cream around your eyes. The Cooling Tip provides a soothing, hygienic application.
Three dots above, three dots belowContinue your regimen
Apply 1-2 pumps of Barrier Balance Cream to the rest of your face. Then finish with 1-2 pumps of the 8-in-1 BioSerum as the final step. The BioSerum goes over everything, including the eye area.
BioSerum goes over everything lastReady for Brighter, Firmer Eyes?
The 3D Eye Radiance Cream PRO Exclusive is available only through authorized medical aesthetic providers. Find one near you.



