


6-Week Perfection Neck Cream
The skin on your neck is thinner, more fragile, and constantly fighting gravity. Deep lines, folds, sagging, and crepiness show up here earlier and progress faster than on your face. This cream was specifically designed to address neck-specific aging with defensin peptides and rich hydration in a formula built just for the neck. Initial results visible in as little as 2 weeks. Full results in 6 to 12 weeks.
Why PRO Exclusive?The PRO Exclusive formulation features an enhanced concentration of Age-Repair Defensins® peptides not available in our retail formulation, designed specifically for the unique needs of neck skin. In DefenAge's peer-reviewed clinical research, the enhanced PRO concentration has been shown to support visible improvement in both the surface and deeper layers of the skin. Available only through your provider's office.
What Are You Seeing on Your Neck?
The neck is one of the first places aging becomes visible. If any of these sound familiar, this cream was designed for you.
Sagging and loss of definition
Your jawline has lost its sharpness. The skin on your neck is drooping and gravity is winning. The contour you used to have is softening and blurring.
Visibly lifts, firms, and tightensDeep horizontal lines and folds
The horizontal creases across your neck are getting deeper. They used to only show when you looked down. Now they're permanent. Makeup and concealer can't hide them.
Smooths deep lines and foldsCrepey, thin skin
The skin on your neck has become paper-thin and wrinkled. It looks crepe-like, fragile, and older than your face. Regular moisturizers don't seem to help.
Improves visible skin thicknessRough, dull texture
Your neck skin has lost its smoothness. It feels rough, looks dull, and has none of the radiance your face might still have. The texture mismatch between your face and neck is obvious.
Softens and brightensAge spots and discoloration
Sun damage on your neck and chest has left dark spots and uneven pigmentation. Your decolletage gives away your age even when your face looks great.
Brightens and improves appearance of spotsTech neck
Hours spent looking down at your phone and laptop are accelerating the creasing and sagging on your neck. The horizontal lines are forming earlier and deeper than they should. Your neck is aging faster than the rest of you because of how you live.
Supports smoother, firmer appearanceBuilt Specifically for Neck Skin
Your neck ages differently than your face. It deserves a formula designed for exactly that.
Designed for how the neck ages
Neck skin is thinner, has fewer oil glands, and is constantly fighting gravity. This cream was specifically formulated for those challenges with defensin peptides in a formula that supports visible lifting and firming. Not a face cream repackaged for the neck.
Fast results you can see
Initial results are noticeable in as little as 2 weeks. The full range of visible improvement, including firmer, smoother, more defined neck contour, develops over 6 to 12 weeks. Luxurious, silky texture that spreads evenly without stickiness.
Gentle on sensitive neck skin
More gentle than retinol on the delicate neck area. Effective for both early and late stages of neck aging. Rich moisturization that nourishes without irritation, from the jawline to the decolletage.
Full Ingredient List — 6-Week Perfection Neck Cream PRO
▾Twice Daily. Lift Up, Not Down.
Cleanse
Cleanse your face, neck, and chest. Leave skin slightly moist from rinsing.
Don't fully dryApply with lifting motions
Place 1 pump of cream onto your fingertips. Using your right hand, apply to the left side of your neck and decolletage with short lifting motions, and vice versa. Start above the breast line and work up to the jawline and back of the neck.
Always lift upwardWait 30 seconds, then finish with BioSerum
Let the cream absorb for 30 seconds, then apply the 8-in-1 BioSerum over the neck area as the final step. The BioSerum delivers eight targeted serums over the neck cream as the final step.
BioSerum locks it inReady to Rediscover Your Neckline?
The 6-Week Perfection Neck Cream PRO Exclusive is available only through authorized medical aesthetic providers. Find one near you.



