Platinum EditionClinically Studied

DefenAge 150K Hair Follicle Serum PRO Exclusive

Platinum Edition

150K Hair Follicle Serum

Your hair has a signal. Don't let it fade.

3 Month SupplyDispenser + 2 refill ampules

1 Month SupplyDispenser with ampule

3 Month Refill3 refill ampules

1 Month Refill1 refill ampule

Your scalp has up to 150,000 hair follicles. Every one of them depends on the right environment to do its job. As you age, the natural signals that support that environment fade. This serum was designed to visibly support the scalp where hair quality begins, with defensin peptides at serum level and more than 30 clinically selected ingredients. No drugs. No hormones. Just science your body already recognizes.

Thinning hairPoor hair growthExcessive sheddingGrey hairScalp healthHair quality

Recommended for

Men & womenThinning hairPost-partum hair changesAge-related changesAll hair types

Why PRO Exclusive?The PRO Exclusive formulation features defensin peptides at serum level paired with more than 30 clinically selected ingredients, each at their studied concentration. This level of formulation, validated in an independent third-party clinical study, is not available in our retail formulation. Available only through your provider's office.

85% of hair shifted to active growth by Day 84 — see the study results

Patented

Drug & hormone free

Give it 90 days

NewBeauty Award Winner

Is this for you?

What Are You Noticing About Your Hair?

Hair changes can be gradual or sudden. If any of these sound familiar, your hair follicles may benefit from the right support.

Thinning hair

Your hair is thinner than it used to be. You can see more scalp, especially along the part. Ponytails are smaller. Hair just doesn't have the volume it once did.

Supports visible hair quality

Excessive shedding

Hair on your pillow, in the shower drain, in your brush. More hair falling out than feels normal. It's been going on for weeks or months and you're worried.

Supports reduced shedding

Poor growth

Your hair grows slowly or seems to have stalled. New growth is fine and weak. It breaks before it gets long enough to style the way you want.

Supports the scalp environment

Grey hair appearing

More grey coming in than you expected. Your natural color is fading faster than you'd like. You're looking for ways to support your hair's natural pigmentation.

Supports the appearance of natural hair color

Scalp issues

Your scalp feels dry, itchy, or irritated. Flaking, inflammation, or discomfort. The environment your hair follicles need to thrive isn't healthy.

Supports scalp wellness

Overall hair quality declining

Your hair looks dull, feels dry, and has lost its shine. The texture has changed. It doesn't look or feel healthy no matter what products you use.

Renews visible hair quality

This product is designed to support the visible improvement and appearance of these conditions. It is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Can be used alongside other hair care treatments your provider may recommend.

Clinically studied

What Happened Over 84 Days

An independent, third-party clinical study tracked hair quality, shedding, and growth over 12 weeks of twice-daily use. Here's what they found.

View clinical studies →

85%

of hair was in the active growth phase at Day 84, up from 25% at baseline

65%

less shedding observed at Day 84 compared to baseline

55%

average improvement in visible hair quality by Day 84

side effects or irritation reported by any participant

Visible increase in hair coverage of the scalp. Day 84. Unretouched clinical photo. Individual results may vary.

Increased hair presence after 84 days of twice-daily use. Unretouched clinical photo. Individual results may vary.

Give it 3 months before you judge

Hair doesn't change overnight. Your hair follicles work on their own timeline, and meaningful visible change takes time. The clinical study measured results at Day 28, Day 56, and Day 84, with the most significant improvements appearing at the 84-day mark. Be consistent, be patient, and give the serum a full 90 days before deciding if it's working for you.

Advanced Science Laboratories, Inc. Report MS22.INUSE.A0771.MTDS.REP. December 2022. Open label study. 4 subjects completed (2 female, 2 male), ages 39-71. 84-day protocol. Twice-daily application. Evaluations at baseline, Day 28, Day 56, and Day 84. Methods: Visual Expert Grading, Maibach Hair Pull, Hair Pluck (Anagen/Telogen Ratio), High Resolution Matched Scientific Photography with Photogrammetrix analysis, optical micrometry. Individual results may vary.

How it works

Supporting the Signals Your Scalp Needs

As you age, the natural signals that support your hair follicle environment fade. This serum was designed to support them.

The Wake-Up Signal

A patented peptide that signals the body to create new and fresh cells by activating the body's dormant reserves. Formulated in 150K to target and optimize the core of hair health and boost visible hair thickness.

The Nourishment Signal

A peptide known as a promoter of capillaries that activates nutrition supply to the hair follicles. Nourishes blood irrigation to create the optimal environment for follicles to flourish.

No drugs. No hormones. Works with everything.

Free from drugs and hormones. Can be used alongside other hair care treatments your provider may recommend. More than 30 clinically selected ingredients, each at their studied concentration. Lightweight, water-based, non-irritating.

Full Ingredient List — 150K Hair Follicle Serum PRO

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Water (Aqua), Pentylene Glycol, Butylene Glycol, Niacinamide, Dimethyl Isosorbide, Caprylic/Capric Triglyceride, Octyldodecanol, Glycerin, Alpha-Defensin 5, Beta-Defensin 3, Hexapeptide-11, Palmitoyl Dipeptide-52, Biotinoyl Tripeptide-1, Biotin, Curcuma Longa (Turmeric) Rhizome Extract, Pisum Sativum (Pea) Sprout Extract, Apium Graveolens (Celery) Seed Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Camellia Sinensis Leaf Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Isochrysis Galbana Extract, Avena Strigosa Seed Extract, Ononis Spinosa Root Extract, Yeast Extract, Ribes Nigrum (Black Currant) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Helianthus Annuus (Sunflower) Seed Oil, Leuconostoc/Radish Root Ferment Filtrate, Betaine, Tocopherol, Tocopheryl Acetate, Ubiquinone, Tocopheryl Nicotinate, Methyl Glucose Sesquistearate, Ammonium Acryloyldimethyltaurate/VP Copolymer, Phospholipids, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, l-Alanyl-l-Glutamine, Maltodextrin, Gellan Gum, Sodium Phytate, Albumin, Sodium Benzoate, Phytic Acid, Potassium Sorbate, Hexylene Glycol, Phenoxyethanol, Sodium Chloride. [ 1-211-1 ]

How to use

Twice Daily. Directly on the Scalp. Leave It On.

Shake and apply

Shake well before first use (cap on). Twice daily, morning and evening, apply 2-3 pumps across your scalp. Press the applicator tip directly onto the scalp and squeeze the wings to release small dots of serum.

Directly on the scalp

Massage into roots

Using your fingertips, gently massage the serum into your hair roots. Concentrate on areas of thinning, poor growth, grey hair, and along the part.

Focus on problem areas

Leave on. Give it 3 months.

Do not rinse. Leave the serum on your scalp. Hair follicles work on their own timeline. Use consistently for a minimum of 90 days before judging your results. The clinical study showed the most meaningful improvements at the 84-day mark. Trust the process.

90 days — then decide

Important: Apply the serum directly onto the scalp and hair roots, not onto the hair itself. The applicator tip is designed to make this easy. Avoid using more pumps than recommended. This is a separate product from your skincare routine and is not layered with the BioSerum or other DefenAge face products.

Available exclusively in-office

Ready to Support Your Hair?

The 150K Hair Follicle Serum PRO Exclusive is available only through authorized medical aesthetic providers. Find one near you.

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